PARP inhibitor News Monitoring

PARP Inhibitors Show Promising Response and Clinical Benefit in BRCA-Altered Uterine Leiomyosarcoma

Patients with BRCA-altered uterine leiomyosarcoma (LMS) treated with PARP inhibitors demonstrated encouraging outcomes, including an overall response rate (ORR) of 46%, a clinical benefit rate (CBR) of 62%, and a median progression-free survival (PFS) of …

Chia Tai Tianqing Pharmaceutical divulges new PARP-1 inhibitors

Next-gen Korean cancer fighters to showcase innovation at ASCO 2025

Korean pharmaceutical and biotech companies are set to present major research milestones at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting, taking place from Friday to Tuesday in Chicago. ASCO, one of the world’s three leading cancer …

New Studies: BRCA1, BRCA2 Mutations Deserve More Attention in Men

Prostate, Pancreatic, Breast Cancer Risks Increased in Male Carriers Male carriers of BRCA1/2 PVs are widely overlooked, even though they also are at increased risk of developing cancer, particularly of the prostate, pancreas and breast. Men represent …

How is metastatic prostate cancer detected and treated in men over 70?

National guidelines on prostate cancer screening with the PSA test are set by the US Preventive Services Task Force (USPSTF). This independent panel of experts in preventive and primary care recommends against screening for prostate cancer in men older …

Hydrogen Sulfide Expression May Affect Ovarian Cancer Progression and Drug Resistance

1Department of Gynaecology, Zhuzhou Central Hospital, Zhuzhou, 412000, People’s Republic of China; 2Department of Central Laboratory, Zhuzhou Central Hospital, Zhuzhou, 412000, People’s Republic of China; 3Department of Transfusion, Zhuzhou Central …

Anticancer Potential of Bioactive Compounds in Premna serratifolia, Premna odorata, and Premna tomentosa: A Review of In ...

Introduction Noncommunicable diseases, characterized by their chronic and complex nature, are responsible for more than 70% of global deaths annually, equating to approximately 41 million fatalities. Among these, cancer ranks as the second leading cause of …

Pan-Cancer Study Reveals DNA Repair Defects

A groundbreaking pan-cancer study published in BMC Cancer unveils the intricate landscape of homologous recombination deficiency (HRD) and homologous recombination repair (HRR) gene alterations across multiple solid tumor types within a vast Asian cohort. …

Polymer Nanoparticles Advancements for Gynecological Cancers

Introduction Nanoparticles (NPs) are solid colloidal particles, usually between 10–1000 nm in size,1 which can be composed of lipids, metals, metal oxides, polymers and other materials.2 Polymer nanoparticles (PNPs) is a collective term for nano-sized …

Analysis of 400,000 Women Validates BRCA Variant Classification

In a monumental advancement for genetic medicine and oncology, a consortium of researchers has published an extensive case-control study analyzing genetic data from over 400,000 women to refine the classification of variants in the BRCA1 and BRCA2 genes. …

ODAC Votes Against Talazoparib Combo for Patients With non-HRR mCRPC

The FDA’s Oncologic Drugs Advisory Committee (ODAC) voted unanimously (8 to 0) against the risk-benefit profile of talazoparib (Talzenna) combined with enzalutamide (Xtandi) for the treatment of patients with metastatic castration-resistant prostate cancer …

IMUNON’s Game-Changing Ovarian Cancer Data Sparks Massive Stock Surge – Here’s What You Need to Know!

Alright, folks, let’s talk about a stock that’s lighting up the market like a Fourth of July fireworks show! As of this writing, IMUNON (NASDAQ: IMNN) is screaming higher, with its stock price soaring by over 230% in pre-market trading on May 23, 2025. …

IMUNON Announces 2025 ASCO Annual Meeting Oral Presentation Highlighting Unprecedented Survival Data from Phase 2 Trial ...

Data show continuous clinically significant improvement, with median 13-month and 3-month increases in overall and progression-free survival, respectively, in treatment group Women treated with IMNN-001 and standard of care chemotherapy plus PARP …

Researchers uncover promising treatment approach for inherited breast cancer

A study led by Addenbrooke’s Hospital in Cambridge has found that a new treatment approach can significantly improve survival rates among patients with aggressive, inherited breast cancers. The research, published in Nature Communications, showed that 100% …

Advancing GPCR drug discovery with fragment screening using GCI technology

G-protein-coupled receptors (GPCRs) play a pivotal role in cellular signaling and have long been a major focus in drug discovery. These receptors regulate a vast array of physiological processes, making them key targets for therapeutic development. Despite …

ASCO: MD Anderson Researchers Present High-Impact Studies Across Multiple Cancers

ABSTRACTS: 11004, 4508, 6503, 11508, 5008 Newswise — CHICAGO, MAY 22, 2025 ― Researchers from The University of Texas MD Anderson Cancer Center will present research at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting. These oral …

Mapping Genetic Risks in Chinese Ovarian Cancer

In a groundbreaking study published in BMC Cancer, researchers have harnessed the power of whole exome sequencing (WES) to unveil the landscape of germline variations associated with ovarian cancer (OC) in a Chinese cohort. The investigation, involving 92 …

Mechanism of Action and Efficacy of Wu-Hua-Yan-Xiao in the Treatment of Pediatric Acute Pharyngitis Based on Network ...

Introduction Acute pharyngitis is among the most common upper respiratory tract infections in children.1 In the United States, approximately 7.3 million children experience pharyngeal pain annually, with acute pharyngitis accounting for 34% of these cases. …

Freedom Confectionery announces B Corp Certification, strengthening its role as the world’s most inclusive sweet brand

Freedom Confectionery announces B Corp Certification, becoming the only brand in its category to meet top ethical, sustainable, and inclusive standards LOS ANGELES, CA, UNITED STATES, May 28, 2025 /⁨EINPresswire.com⁩/ -- Freedom Confectionery LLC, …

Genetic Testing Market to Witness Robust Growth at a CAGR of 23.1% by 2033 | DataM Intelligence

Genetic Testing Market- Innovative technologies, shifting patient preferences, and supportive government policies fuel market expansion across key regions CALIFORNIA, CA, UNITED STATES, May 29, 2025 /⁨EINPresswire.com⁩/ -- The global genetic …

Nourify & Beautify Podcast Unveils New Logo, Website; Invites Nutraceutical and Cosmetic Founders to Be Featured Guests

Nourify & Beautify launches a new look, opens guest slots for founders, and invites subscribers to join its mission for safer, smarter beauty and wellness. IRVINE, CA, UNITED STATES, May 28, 2025 /⁨EINPresswire.com⁩/ -- Nourify & Beautify, …

Kent County High School Art Society Students Deck the Halls at Chestertown Nursing and Rehab

Kent County High School Art Society Students Deck the Halls at Chestertown Nursing and Rehab MARLTON, NJ, UNITED STATES, May 28, 2025 /⁨EINPresswire.com⁩/ -- About a dozen art society students from Kent County High School spent the afternoon at …

Evident and XDENT LAB Announce Integration to Support Diversified Outsourcing for Dental Labs

VANCOUVER, BRITISH COLUMBIA, CANADA, May 28, 2025 /⁨EINPresswire.com⁩/ -- Evident has announced a new integration with XDENT LAB, a Vietnam-based dental lab that provides full-service lab-to-lab fabrication. The partnership enables dental labs …

NeoHack Life Sciences Granted Patent by USPTO for Compositions and Methods of Achieving Pain Relief

Patent Claims include Alzheimer's Disease, Crohn's, Arthritis and Multiple Other Chronic Inflammatory Conditions SCOTTSDALE, AZ, UNITED STATES, May 28, 2025 /⁨EINPresswire.com⁩/ -- NeoHack Life Sciences Granted Patent by USPTO, Confirms …

Blue Goat Cyber Reaches Milestone: 21 Episodes of The Med Device Cyber Podcast Now Available

21 episodes in, The Med Device Cyber Podcast continues to empower MedTech teams with expert insights on cybersecurity, FDA compliance, and patient safety. SCOTTSDALE, AZ, UNITED STATES, May 28, 2025 /⁨EINPresswire.com⁩/ -- Blue Goat Cyber, a …

Mindful Connections Therapy Announces New Ketamine Assisted Therapy Services in Tucson, AZ

Mindful Connections Therapy is proud to announce the launch of its new Ketamine Assisted Therapy services. TUCSON, AZ, UNITED STATES, May 28, 2025 /⁨EINPresswire.com⁩/ -- Mindful Connections Therapy, a leading provider of mental health services in …

CareRite Centers Celebrates 11th Annual Nursing Home Week: Under the Sea: Navigating the 4 C’s of #TheCareRiteDifference

ENGLEWOOD CLIFFS, NJ, UNITED STATES, May 28, 2025 /⁨EINPresswire.com⁩/ -- CareRite Centers proudly celebrated its 11th Annual National Nursing Home Week from May 12th to May 16th, 2025, across its network in New York, New Jersey, Florida, and …

Tele911 and Dune Health Launch First-of-Its-Kind Emergency Care Partnership Powered by Wearable Data

With Tele911 Connect Plus, Patients Get Emergency Physician Access in Minutes - No 911 Call Required. PASADENA, CA, UNITED STATES, May 28, 2025 /⁨EINPresswire.com⁩/ -- Tele911, the national leader in virtual emergency medicine, today announced a …

GCRC's Mike Robinson Joins Organizing Committee for Dubai's Global Breast Cancer Treatment Conference

Robinson is known around the world for his nonstop education on the Endocannabinoid System (ECS), and his willingness to help educate the Healthcare Industry SANTA BARBARA, CA, UNITED STATES, May 28, 2025 /⁨EINPresswire.com⁩/ -- Mike Robinson, …

Master Resilience Training/Training Center Support (MRT/TCS)

VIENNA, VA, UNITED STATES, May 28, 2025 /⁨EINPresswire.com⁩/ -- Strategic Resources, Inc. (SRI) is proud to announce it has won a contract in support of the U.S. Army G-9’s, Directorate of Prevention, Resilience and Readiness (DPRR) to provide …

Prime Experiences Launches Corporate Memberships And Expands Yacht Event Offerings In Miami

From B2B yacht activations to curated cruises, Prime Experiences introduces a membership program for Miami’s fast-growing corporate event market. MIAMI, FL, UNITED STATES, May 28, 2025 /⁨EINPresswire.com⁩/ -- PRIME EXPERIENCES LAUNCHES CORPORATE …

NCHE Cites Importance of New Campaign Addressing Drug Overdose Crisis In Black Communities

The You Have the Power to Save Lives campaign is increasing access to naloxone and empowering Black communities with the knowledge and tools to save lives WASHINGTON, DC, UNITED STATES, May 28, 2025 /⁨EINPresswire.com⁩/ -- The National …

Growing Healthcare Costs Disproportionately Affect Over 70 Million Disabled Americans

Enhanced training and new developments in software improve health outcomes and decrease healthcare costs. CLEARWATER, FL, UNITED STATES, May 28, 2025 /⁨EINPresswire.com⁩/ -- As healthcare spending remains at an all-time high, the cost of care for …

BestRx Pharmacy Software Announces Integration with Lansworth Pharma SelfServe’s Pharmaself24 Kiosk Solution

BestRx is pleased to announce a new integration with Lansworth Pharma SelfServe, an advanced automated prescription pickup solution. OAKBROOK, IL, UNITED STATES, May 28, 2025 /⁨EINPresswire.com⁩/ -- BestRx, a RedSail Technologies company and a leading …

Three Unique Phoenix Med Spas Redefining Beauty Care

Analysis details three Phoenix med spas adopting tech-enabled, safety-focused care as Arizona med-spa revenue climbs 13% since 2022. PHOENIX, AZ, AZ, UNITED STATES, May 28, 2025 /⁨EINPresswire.com⁩/ -- Phoenix’s med‑spa sector has moved from niche to …

Pictor Labs and PathPresenter Partner to Bring AI-Powered Virtual Stains to the Digital Pathology Community

LOS ANGELES, CA, UNITED STATES, May 28, 2025 /⁨EINPresswire.com⁩/ -- Pictor Labs, a leader in AI-driven virtual histochemical staining, today announced a strategic partnership with PathPresenter, a leading Image Management System and workflow …

Federal Court Awards Compensation to Vaccine Injury Victim Represented by Knutson Casey

SIRVA injury to Shoulder Compensated by Vaccine Court MANKATO, MN, UNITED STATES, May 28, 2025 /⁨EINPresswire.com⁩/ -- In a significant legal victory for vaccine injury victims, the United States Court of Federal Claims has ruled in favor of …

From Fear to Love Tour Brings Trauma-Informed Parenting Workshop to Fresno, CA on June 11

FRESNO, CA, UNITED STATES, May 28, 2025 /⁨EINPresswire.com⁩/ -- On June 11, 2025, nationally recognized parenting expert Bryan Post will bring his From Fear to Love World Tour to Fresno, California, for a live, in-person trauma-informed parenting …